Hospital-based surveillance of invasive pneumococcal disease and pneumonia in South Bangalore, India.
نویسندگان
چکیده
OBJECTIVE To estimate the incidence of invasive pneumococcal disease and pneumonia, distribution of pneumococcal serotypes, and antibiotic susceptibility in children aged 28 days to <60 months. DESIGN Hospital-based surveillance. SETTING South Bangalore, India. PARTICIPANTS 9950 children aged 28 days to <60 months with clinical suspicion of invasive pneumococcal disease or pneumonia. RESULTS The estimated at-risk population included 224,966 children <5 years of age. Forty cases of invasive pneumococcal disease were identified. Estimated invasive pneumococcal disease incidence was 17.8/100,000 with incidence being highest among children aged 6 months to <12 months (49.9/100,000). Clinical pneumonia syndrome was the most frequent diagnosis (12.5/100,000). Pneumococcal serotypes included: 6A (n=6, 16.7%); 14 (n=5, 13.9%); 5 (n=4, 11.1%); 6B (n=4, 11.1%); 1, 18C, and 19A (n=3 each, 8.3%); 9V (n=2, 5.6%); and 3, 4, 10C, 18A, 18F, and 19F (n=1 each, 2.8%). Serotypes 6A, 14, 6B, 1, 18C, 19A, 9V, 4, 10C, and 18A showed antibiotic resistance. Clinical pneumonia incidence was 2109/100,000, with incidence being highest among children aged 28 days to <6 months (5033/100,000). Chest radiograph-confirmed pneumonia incidence was 1114/100,000, with incidence being highest among children aged 28 days to <6 months (2413/100,000). CONCLUSIONS Invasive pneumococcal disease and pneumonia were found to be common causes of morbidity in young children living in South Bangalore, India.
منابع مشابه
Establishment of population-based surveillance for invasive pneumococcal disease in Bangalore, India.
BACKGROUND Invasive pneumococcal disease (IPD) is vaccine-preventable but few data on the incidence of PD exist for Indian children. AIMS To assess the feasibility of implementing prospective, population-based surveillance for PD among children less than five years of age. Settings and Design :Hospitals and health agencies, Bangalore, India. Retrospective review and analysis of hospitalizatio...
متن کاملInvasive pneumococcal disease and India.
1. Thomas K. Prospective multicentre hospital surveillance of Streptococcus pneumoniae disease in India. Invasive Bacterial Infection Surveillance (IBIS) Group, International Clinical Epidemiology Network (INCLEN). Lancet. 1999;353:1216-21. 2. Shah AS, Nisarga R, Ravi Kumar KL, Hubler R, Herrera G, Kilgore PE. Establishment of population-based surveillance for invasive pneumococcal disease in B...
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Limited information is available on the outline of invasive diseases caused by Streptococcus pneumoniae among the underprivileged children in India. Estimation of Invasive Pneumococcal Disease (IPD) and Pneumonia depends mainly on hospital-based clinical surveillance data. Data on serotype prevalence and antimicrobial resistance of IPD have been documented in some studies in India [1-4]. Due to...
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OBJECTIVE The primary objective was to estimate the burden of invasive pneumococcal disease (IPD) in children aged 1 month to 12 years in South Asian countries. METHODS We searched three electronic databases (PubMed, Embase and the Cochrane Library) using a comprehensive search strategy, we manually searched published databases (Index Medicus and Current Contents) and we also searched the bib...
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ورودعنوان ژورنال:
- Indian pediatrics
دوره 52 3 شماره
صفحات -
تاریخ انتشار 2015